Genetic Mutation Increases Risk of Parkinson's Disease from Pesticides


(December 2, 2013) - A team of researchers has brought new clarity to the picture of how gene-environmental interactions can kill nerve cells that make dopamine. For the first time, they have used human stem cells derived from Parkinson's disease patients to show that a genetic mutation combined with exposure to pesticides creates a 'double hit' scenario, producing free radicals in neurons that disable specific molecular pathways that cause nerve-cell death. Read more…

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